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货号： bs-18361R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18361R-AF555
- 英文名称
- Anti-LRP11/AF555
- 中文名称
- AF555标记的低密度脂蛋白受体相关蛋白11抗体
- 别 名
- bA350J20.3; Low density lipoprotein receptor related protein 11; LRP 11; MANSC3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 49kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LRP11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
LRP11 is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25.1. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinsons disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Function:
LRP11 belongs to the LDLR family. It contains one LDL-receptor class A domain, one MANEC domain and one PKD domain. There are two named isoforms.
Subcellular Location:
Membrane; Single pass type I membrane protein
Similarity:
Belongs to the LDLR family.
Contains 1 LDL-receptor class A domain.
Contains 1 MANSC domain.
Contains 1 PKD domain.
Database links:Entrez Gene: 84918Human
SwissProt: Q86VZ4Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.