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货号： bs-18313R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18313R-AF555
- 英文名称
- Anti-LMO1/AF555
- 中文名称
- AF555标记的T淋巴细胞转运蛋白1抗体
- 别 名
- Cysteine rich protein TTG 1; Cysteine rich protein TTG1; LIM domain only 1; LIM domain only protein 1; LMO 1; MGC116692; RBTN 1; RBTN1; RHOM 1; RHOM1; Rhombotin 1; Rhombotin1; T cell translocation protein 1; TTG 1; TTG1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转运蛋白 淋巴细胞 t-淋巴细胞 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Zebrafish, Guinea Pig, Monkey, Cat, Spider Monkey
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LMO1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]
Function:
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.
Subcellular Location:
Nuclear
Tissue Specificity:
Expressed mainly in the central nervous. Low level of expression in other tissues including thymus.
DISEASE:
A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD.
Similarity:
Contains 2 LIM zinc-binding domains.
Database links:Entrez Gene: 27152Cow
Entrez Gene: 4004Human
Entrez Gene: 109594Mouse
Entrez Gene: 245979Rat
Entrez Gene: 280646Zebrafish
Omim: 186921Human
SwissProt: Q0P5B3Cow
SwissProt: P25800Human
SwissProt: Q924W9Mouse
SwissProt: Q8JFQ2Zebrafish
Unigene: 654426Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.