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货号： bs-18307R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18307R-AF555
- 英文名称
- Anti-LMAN2L/VIPL/AF555
- 中文名称
- AF555标记的凝集素甘露糖结合蛋白2样蛋白抗体
- 别 名
- DKFZp564L2423; Lectin mannose-binding 2-like; lectin, mannose binding 2 like; LMA2L_HUMAN; LMAN2 like protein; LMAN2-like protein; LMAN2L; MGC11139; VIP36 like protein [Precursor]; VIP36-like protein; VIPL.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LMAN2L/VIPL
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Lectin mannose-binding 1, also designated vesicular integral-membrane protein (VIP36), and lectin mannose-binding 2, also designated ERGIC-53, comprise a family of membrane bound, ubiquitously expressed proteins involved in the selective transport of newly synthesized glycoproteins from the endoplasmic reticulum to the ER-Golgi intermediate compartment. VIPL (VIP36-like protein), also known as LMAN2L (lectin, mannose-binding 2-like), is a 348 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and Golgi apparatus. Containing one L-type lectin-like domain, VIPL is highly expressed in skeletal muscle and kidney, and is found at intermediate levels in heart, liver and placenta, and low levels in brain, thymus, spleen, small intestine and lung. VIPL is suggested to be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. VIPL may function as a regulator of ERGIC-53. VIPL exists a two alternatively spliced isoforms.
Function:
May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53.
Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane. Predominantly found in the endoplasmic reticulum. Partly found in the Golgi.
Tissue Specificity:
Expressed in numerous tissues. Highest expression in skeletal muscle and kidney, intermediate levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung.
Similarity:
Contains 1 L-type lectin-like domain.
Database links:Entrez Gene: 81562Human
Entrez Gene: 214895Mouse
Entrez Gene: 301343Rat
Omim: 609552Human
SwissProt: Q9H0V9Human
SwissProt: P59481Mouse
Unigene: 655743Human
Unigene: 287854Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.