产品中心
当前位置：首页>产品中心Anti-SIDT2/AF555
货号： bs-17485R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17485R-AF555
- 英文名称
- Anti-SIDT2/AF555
- 中文名称
- AF555标记的SIDT2蛋白抗体
- 别 名
- SIDT-2;B930096O19; BC023957; CGI 40; DKFZp686L17253; FLJ90656; MGC36407; MGC58967; RGD1308311; SID1 transmembrane family member 2; SID1 transmembrane family, member 2; SIDT2; SIDT2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 通道蛋白 跨膜蛋白 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 93kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SIDT2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.
Subcellular Location:
Lysosome membrane.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the SID1 family.
Database links:Entrez Gene: 51092Human
Entrez Gene: 214597Mouse
Entrez Gene: 315617Rat
SwissProt: Q8NBJ9Human
SwissProt: Q8CIF6Mouse
SwissProt: D3ZEH5Rat
Unigene: 712144Human
Unigene: 379345Mouse
Unigene: 162997Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.