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货号： bs-17353R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17353R-AF555
- 英文名称
- Anti-Homez/AF555
- 中文名称
- AF555标记的同源盒亮氨酸拉链蛋白HOMEZ抗体
- 别 名
- Homeobox and leucine zipper protein Homez; Homeodomain leucine zipper containing factor; KIAA1443.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 结合蛋白 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Homez
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney.
Function:
Homez and members of ZHX family of zinc finger homeodomain factors are delineated as a subset within the superfamily of homeobox-containing proteins.
Subcellular Location:
Nuclear
Database links:Entrez Gene: 57594Human
Entrez Gene: 239099Mouse
Entrez Gene: 260325Rat
Omim: 608119Human
SwissProt: Q8IX15Human
SwissProt: Q504Z8Mouse
SwissProt: Q80W88Mouse
SwissProt: Q5XFX1Rat
SwissProt: Q8K3E9Rat
Unigene: 52743Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.