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货号： bs-17206R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17206R-AF555
- 英文名称
- Anti-Josephin-1/AF555
- 中文名称
- AF555标记的JOSD1蛋白抗体
- 别 名
- dJ508I15.2; JOS1_HUMAN; Josd1; Josephin 1; Josephin domain containing 1; Josephin domain-containing 1; Josephin-1; KIAA0063; OTTHUMP00000198984; OTTHUMP00000239365.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 发育生物学 泛素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Cat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human JOSD1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Josephin-1 is a 202 amino acid protein that contains one josephin domain and is encoded by a gene that maps to human chromosome 22. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
Function:
Has low protease activity towards poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme.
Subunit:
Interacts with beta-actin/ACTB.
Similarity:
Contains 1 Josephin domain.
Database links:Entrez Gene: 9929Human
Entrez Gene: 74158Mouse
Entrez Gene: 315134Rat
SwissProt: Q15040Human
SwissProt: Q9DBJ6Mouse
SwissProt: Q5BJY4Rat
Unigene: 3094Human
Unigene: 2495Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.