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货号: bs-17199R-AF555 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-17199R-AF555
- 英文名称
- Anti-Jaw1/AF555
- 中文名称
- AF555标记的淋巴限制膜蛋白Jaw1抗体
- 别 名
- Lrmp; LRMP_HUMAN; Lymphoid restricted membrane protein; Lymphoid restricted membrane protein; Processed lymphoid-restricted membrane protein; Protein Jaw1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 62kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Jaw1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Function:
Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.
Subunit:
Interacts (via coiled-coil domain) with ITPR3.
Subcellular Location:
Cytoplasm and Endoplasmic reticulum membrane.
Tissue Specificity:
Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells.
Post-translational modifications:
The removal of the C-terminal lumenal domain occurs by proteolytic processing.
Database links:Entrez Gene: 4033Human
Omim: 602003Human
SwissProt: Q12912Human
Unigene: 124922Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.