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货号： bs-17066R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17066R-AF555
- 英文名称
- Anti-Kinesin C2/AF555
- 中文名称
- AF555标记的驱动蛋白家族成员C2抗体
- 别 名
- KIF C2; KIFC 2; KIFC2; KIFC2 protein; KIFC2_HUMAN; Kinesin family member C2; Kinesin like protein KIFC2; Kinesin-like protein KIFC2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 90kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Kinesin C2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination, and speed of transportation of a variety of important functional molecules, including mRNA. KIFC2 is 792 amino acid member of the C-terminal motor family specifically expressed in both the central and peripheral nervous systems in nonproliferative cells. KIFC2 accumulates at the proximal and distal sides of axons and is a minus-end-directed kinesin. KIFC2 localizes with some, but not all, axonally transported organelles. KIFC2 may be involved in retrograde axonal transport.
Function:
May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites.
Subcellular Location:
Cytoplasm; cytoskeleton.
Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.
Database links:Entrez Gene: 90990Human
Entrez Gene: 16581Mouse
Entrez Gene: 300053Rat
SwissProt: Q96AC6Human
SwissProt: O08672Mouse
Unigene: 528713Human
Unigene: 378950Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.