产品中心
当前位置：首页>产品中心Anti-KCTD1/AF555
货号： bs-16924R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16924R-AF555
- 英文名称
- Anti-KCTD1/AF555
- 中文名称
- AF555标记的钾离子通道多聚体结构域蛋白1抗体
- 别 名
- BTB/POZ domain-containing protein KCTD1; C18orf5; Kctd1; KCTD1_HUMAN; Potassium channel tetramerisation domain containing 1; Potassium channel tetramerization domain-containing protein 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KCTD1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
KCTD1 (potassium channel tetramerisation domain containing 1), also known as C18orf5, is a 257 amino acid protein that contains one BTB domain, suggesting an involvement in transcriptional control. The gene encoding KCTD1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
Function:
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in mammary gland, kidney, brain and ovary.
Post-translational modifications:
Sumoylated.
Similarity:
Contains 1 BTB (POZ) domain.
Database links:Entrez Gene: 284252Human
Omim: 613420Human
SwissProt: Q719H9Human
Unigene: 526630Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.