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货号： bs-16918R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16918R-AF555
- 英文名称
- Anti-KCNS3/AF555
- 中文名称
- AF555标记的电压门控钾通道亚基KV9.3抗体
- 别 名
- Delayed rectifier K(+) channel alpha subunit 3; Delayed rectifier K+ channel alpha subunit 3; Delayed-rectifier K(+) channel alpha subunit 3; KCNS 3; Kcns3; KCNS3_HUMAN; KV 9.3; KV9.3; MGC9481; Potassium voltage gated channel delayed rectifier protein S3; Potassium voltage gated channel delayed rectifier subfamily S member 3; Potassium voltage gated channel subfamily S member 3; Potassium voltage-gated channel subfamily S member 3; Shab related delayed rectifier K+ channel alpha subunit 3; Voltage gated potassium channel subunit Kv9.3; Voltage-gated potassium channel subunit Kv9.3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 通道蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KCNS3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]
Function:
Potassium channel subunit. Modulates channel activity and reduces the ion flow.
Subunit:
Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins (By similarity).
Subcellular Location:
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
Tissue Specificity:
Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.
Similarity:
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
Database links:Entrez Gene: 3790Human
Entrez Gene: 238076Mouse
Entrez Gene: 83588Rat
Omim: 603888Human
SwissProt: Q9BQ31Human
SwissProt: Q8BQZ8Mouse
SwissProt: O88759Rat
Unigene: 414489Human
Unigene: 113278Mouse
Unigene: 10878Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.