产品中心
当前位置：首页>产品中心Anti-GPCR GPR6/AF555
货号： bs-16262R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16262R-AF555
- 英文名称
- Anti-GPCR GPR6/AF555
- 中文名称
- AF555标记的G蛋白偶联受体6抗体
- 别 名
- G protein coupled receptor 6; GPR 6; GPR6; GPR6_HUMAN; Sphingosine 1 phosphate receptor GPR 6; Sphingosine 1 phosphate receptor GPR6.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GPCR GPR6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR6 is a member of this family (subfamily lysophospholipid/lysosphingolipid). GPR6 has been reported to be expressed in brain, particularly in the putamen, and to a lesser extent, in the frontal cortex, hippocampus, and hypothalamus. An EST has been isolated from a human brain (hypothalamus) library. GPCR GPR6 belongs to the G-protein coupled receptor 1 family. It is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 2830Human
Entrez Gene: 140741Mouse
Entrez Gene: 83683Rat
Omim: 600553Human
SwissProt: P46095Human
SwissProt: Q6YNI2Mouse
SwissProt: P51651Rat
Unigene: 46332Human
Unigene: 32092Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.