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货号： bs-16099R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16099R-AF555
- 英文名称
- Anti-FMO4/AF555
- 中文名称
- AF555标记的肝黄素单加氧酶4抗体
- 别 名
- Flavin containing monooxygenase 4;Dimethylaniline monooxygenase [N oxide forming] 4; Dimethylaniline monooxygenase [N-oxide-forming] 4; Dimethylaniline monooxygenase 4; Dimethylaniline oxidase 4; FMO 2; FMO 4; FMO2; Fmo4; FMO4_HUMAN; Hepatic flavin containing monooxygenase 4; Hepatic flavin-containing monooxygenase 4; OTTHUMP00000060454.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 63kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FMO4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Sep 2013]
Function:
This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.
Subcellular Location:
Microsome membrane. Endoplasmic reticulum membrane.
Tissue Specificity:
Liver.
Similarity:
Belongs to the FMO family.
Database links:Entrez Gene: 2329Human
Omim: 136131Human
SwissProt: P31512Human
Unigene: 386502Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.