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货号： bs-16006R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16006R-AF555
- 英文名称
- Anti-FAM58A/AF555
- 中文名称
- AF555标记的FAM58A蛋白抗体
- 别 名
- Cyclin-M; Cyclin-related protein FAM58A; FA58A_HUMAN; Fam58a; Family with sequence similarity 58 member A; STAR.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 28kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FAM58A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FAM58A (family with sequence similarity 58, member A) and FAM58B (family with sequence similarity 58, member B) are 248 amino acid and 252 amino acid proteins, respectively, that belong to the cyclin-like FAM58 subfamily. Existing as multiple alternatively spliced isoforms, FAM58A interacts with Sall1 and is thought to play a role in cellular proliferation. Defects in the gene encoding FAM58A are associated with toe syndactyly, telecanthus, and anogenital and renal malformations (STAR syndrome), which is characterized by renal and anogenital malformations. FAM58B, a protein that is related to FAM58A, is expressed in healthy retina and breast tissue, as well as in retinoblastoma and breast cancer cell lines, suggesting a role for FAM58B in tumor transformation and metastasis.
Function:
May have a role in cell proliferation.
DISEASE:
Toe syndactyly, telecanthus, and anogenital and renal malformations
Similarity:
Belongs to the cyclin family. Cyclin-like FAM58 subfamily.
Database links:Entrez Gene: 92002Human
Entrez Gene: 303321Rat
Omim: 300708Human
SwissProt: Q8N1B3Human
SwissProt: Q4QQW5Rat
Unigene: 496943Human
Unigene: 38890Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.