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货号: bs-14678R-AF555 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-14678R-AF555
- 英文名称
- Anti-FA83D/AF555
- 中文名称
- AF555标记的FA83D蛋白抗体
- 别 名
- 2310007D09Rik; BB104611; C20orf129; CHICA; dJ616B8.3; FA83D_HUMAN; FAM83D; Family with sequence similarity 83, member D; FLJ38341; MGC92947; Protein FAM83D; RGD1565583; RP23-119H5.1; Spindle protein CHICA.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 64kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FA83D
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis which are thought important for seminal production and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The FAM83D gene product has been provisionally designated FAM83D pending further characterization.
Function:
Required for proper chromosome congression and alignment during mitosis. Required for targeting KIF22/KID to the spindle microtubules.
Subcellular Location:
Cytoplasm. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Primarily cytoplasmic during interphase, but beginning in prophase, associates with spindle microtubules, with a clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase.
Similarity:
Belongs to the FAM83 family.
Database links:Entrez Gene: 81610Human
SwissProt: Q9H4H8Human
Unigene: 726442Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.