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货号： bs-14540R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14540R-AF555
- 英文名称
- Anti-EIF2G/AF555
- 中文名称
- AF555标记的EIF2G蛋白抗体
- 别 名
- eIF-2-gamma X; eIF-2gA; eIF-2gX; EIF2; EIF2G; EIF2gamma; Eif2s3; Eukaryotic translation initiation factor 2 gamma; Eukaryotic translation initiation factor 2 gamma subunit; Eukaryotic translation initiation factor 2 subunit 3; Eukaryotic translation initiation factor 2 subunit 3 gamma 52kDa; Eukaryotic translation initiation factor 2 subunit gamma X; IF2G_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转运蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EIF2G
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]
Function:
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B
Subunit:
Heterotrimer composed of an alpha, a beta and a gamma chain.
Similarity:
Belongs to the GTP-binding elongation factor family. EIF2G subfamily.
Database links:Entrez Gene: 1968Human
Entrez Gene: 26905Mouse
Entrez Gene: 26908Mouse
Entrez Gene: 100312984Rat
Entrez Gene: 299027Rat
Omim: 300161Human
SwissProt: P41091Human
SwissProt: Q9Z0N1Mouse
SwissProt: P81795Rat
Unigene: 539684Human
Unigene: 218851Mouse
Unigene: 250909Mouse
Unigene: 220237Rat
Unigene: 87025Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.