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货号： bs-14263R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14263R-AF555
- 英文名称
- Anti-Delta 1 Tubulin/AF555
- 中文名称
- AF555标记的微管蛋白δ1/δ Tubulin抗体
- 别 名
- Delta tubulin; Delta-tubulin; FLJ12709; TBD_HUMAN; TUBD; TUBD1; Tubulin delta chain.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Delta 1 Tubulin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. GammaTubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and Delta Tubulin are associated with the centrosome. Gamma Tubulin is a homolog of the Chlamydomonas Gamma Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. Delta Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Function:
In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.
Subcellular Location:
Cytoplasm > cytoskeleton > centrosome > centriole. Cytoplasm. Nucleus. Associated with centrioles. Both cytoplasmic and nuclear.
Similarity:
Belongs to the tubulin family.
Database links:Entrez Gene: 51174Human
Omim: 607344Human
SwissProt: Q9UJT1Human
Unigene: 463638Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.