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货号： bs-14203R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14203R-AF555
- 英文名称
- Anti-DBNDD2/CK1BP/AF555
- 中文名称
- AF555标记的酪蛋白激酶1结合蛋白抗体
- 别 名
- C20orf35; Casein kinase-1 binding protein; CK1BP; DBND2_HUMAN; Dbndd2; Dysbindin (dystrobrevin binding protein 1) domain containing 2; Dysbindin domain-containing protein 2; HSMNP1; SCF apoptosis response protein 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 28kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DBNDD2/CK1BP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
CK1BP is a 261 amino acid member of the dysbindin family and is a paralog of dysbindin, a protein trafficking protein involved in lysosome biosynthesis that has been associated with schizophrenia and muscular dystrophy. Human and rat HSMNP1 share 86% identity and both proteins contain three casein kinase II and PKC (protein kinase C) phosphorylation sites, a putative N-glycosylation site and a PEST motif at the C-terminus. HSMNP1 is a cytoplasmic protein and it specifically localizes to vesicles during the induction of apoptosis. In addition, HSMNP1 may be involved in normal as well as pathological myeloid development. Two isoforms of HSMNP1 exist due to alternative splicing events.
Function:
May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).
Tissue Specificity:
Detected in brain.
Similarity:
Belongs to the dysbindin family.
Database links:Entrez Gene: 55861Human
Omim: 611453Human
SwissProt: Q9BQY9Human
Unigene: 655055Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.