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货号： bs-14150R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14150R-AF555
- 英文名称
- Anti-CYP2C18/AF555
- 中文名称
- AF555标记的细胞色素P450 2C18抗体
- 别 名
- (S) mephenytoin hydroxylase associated cytochrome P450; CPCI; CYP2C 18; CYP2C; CYP2C17; CP2CI_HUMAN; CYPIIC18; Cytochrome P450 2C18; Cytochrome P450 6B/29C; Cytochrome P450 family 2 subfamily C polypeptide 18; Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 17; Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 18; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 6B/29C; P450IIC17; Unspecific monooxygenase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CYP2C18
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Database links:Entrez Gene: 1562Human
Omim: 601131Human
SwissProt: P33260Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.