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货号： bs-14138R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14138R-AF555
- 英文名称
- Anti-Cyclophilin E/AF555
- 中文名称
- AF555标记的亲环蛋白（亲环素）E抗体
- 别 名
- Ab1-210; Cyclophilin 33; Cyclophilin E; Cyclophilin-33; CYP 33; CYP33; EC 5.2.1.8; Peptidyl prolyl cis trans isomerase E; Peptidyl-prolyl cis-trans isomerase E; Peptidylprolyl isomerase E (cyclophilin E); Peptidylprolyl isomerase E; PPIase E; PPIE; PPIE_HUMAN; Rotamase E.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Cyclophilin E
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Combines RNA-binding and PPIase activities. May be involved in muscle- and brain-specific processes. May be involved in pre-mRNA splicing.
Subcellular Location:
Nucleus.
Tissue Specificity:
Found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Similarity:
Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
Contains 1 PPIase cyclophilin-type domain.
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 10450Human
Entrez Gene: 787681Cow
Entrez Gene: 56031Mouse
Entrez Gene: 298508Rat
Omim: 602435Human
SwissProt: A4FV72Cow
SwissProt: Q9UNP9Human
SwissProt: Q9QZH3Mouse
Unigene: 524690Human
Unigene: 126873Mouse
Unigene: 18887Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.