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货号： bs-10617R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10617R-AF555
- 英文名称
- Anti-Troponin I fast + slow skeletal muscle /AF555
- 中文名称
- AF555标记的骨骼肌快/慢肌肌钙蛋白I抗体
- 别 名
- AMCD2B; DA2B; DKFZp451O223; Fast twitch skeletal muscle troponin I; FSSV; fsTnI; OTTHUMP00000014141; OTTHUMP00000014142; OTTHUMP00000014143; OTTHUMP00000033877; OTTHUMP00000033909; OTTHUMP00000033910; SSTNI; TNN1; Troponin I fast twitch 2; Troponin I type 1 (skeletal, slow); Troponin I type 2 (skeletal, fast); Troponin I, fast skeletal muscle; Troponin I, fast twitch isoform; Troponin I, fast twitch skeletal muscle isoform; Troponin I, skeletal, fast; Troponin I, slow skeletal muscle; Troponin I, slow twitch isoform; TNNI1_HUMAN; TNNI2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 细胞骨架
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Chicken, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TNNI1+TNNI2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue.
Function:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Subunit:
Binds to actin and tropomyosin.
DISEASE:
Arthrogryposis, distal, 2B (DA2B) [MIM:601680]: A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2B is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the troponin I family.
Database links:Entrez Gene: 7135 Human
Entrez Gene: 7136 Human
Omim: 191042 Human
Omim: 191043 Human
SwissProt: P19237 Human
SwissProt: P48788 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.