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货号： bs-15410R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15410R-AF555
- 英文名称
- Anti-HAPLN1 /AF555
- 中文名称
- AF555标记的透明质酸及粘蛋白1抗体
- 别 名
- Cartilage link protein; cartilage linking protein 1; CLP; CRTL1; Crtl1l; hyaluronan and proteoglycan link protein 1; Hyaluronan and proteoglycan link protein 1 precursor; LP; Proteoglycan link protein; HPLN1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导 细菌及病毒 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HAPLN1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The human cartilage link protein, also designated HAPLN1, is a member of the hyaluronan and proteoglycan link protein (HAPLN) family of proteins. This family contains 4 proteins with approximately 50% homology. The human cartilage link protein strengthens tissue architecture by using hyaluronic acid to stabilize the aggregates of proteoglycan monomers inside the extracellular cartilage matrix. It is widely expressed in most tissue types except brain tissue where, much like the other human cartilage link protein genes, it is weakly expressed. The HAPLN and the brain-specific CSPG genes, as well as other members of the link module superfamily, appear to have a common ancestral gene origin.
Function:
Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
Subcellular Location:
Secreted, extracellular space, extracellular matrix.
Tissue Specificity:
Widely expressed. Weakly expressed in the brain.
Similarity:
Belongs to the HAPLN family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Contains 2 Link domains.
Database links:
UniProtKB/Swiss-Prot: P10915.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.