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货号： bs-15393R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15393R-AF555
- 英文名称
- Anti-GPRASP2/AF555
- 中文名称
- AF555标记的G蛋白偶联受体GPRSP2蛋白抗体
- 别 名
- FLJ35662; FLJ37327; G-protein coupled receptor-associated sorting protein 2; GASP-2; GASP2; GPRASP2; GASP2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 94kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GPRASP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
G protein-coupled receptors play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GASP-2 (G protein-coupled receptor associated sorting protein 2), also known as GPRASP2, is an 838 amino acid protein that regulates a number of G-protein coupled receptors, such as CT-R (calcitonin receptor) and mAChR M1 (muscarinic acetylcholine receptor M1), through interactions with their cytoplasmic tails. Expressed primarily in brain, GASP-2 is a member of the GPRASP family and forms a complex with Huntingtin, with which it is thought to influence receptor trafficking.
Function:
May play a role in regulation of a variety of G-protein coupled receptors.
Subunit:
Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1 and calcitonin receptor/CALCR.
Subcellular Location:
Cytoplasmic
Tissue Specificity:
Expressed in the brain.
Similarity:
Belongs to the GPRASP family.
Database links:Entrez Gene: 114928Human
Entrez Gene: 245607Mouse
GenBank: NP_001004051Human
SwissProt: Q96D09Human
SwissProt: Q8BUY8Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.