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货号： bs-11747R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11747R-AF555
- 英文名称
- Anti-Puratrophin 1/AF555
- 中文名称
- AF555标记的浦肯野细胞萎缩相关蛋白1抗体
- 别 名
- ARHGEF44; PH domain-containing family G member 4; PKHG4_HUMAN; Pleckstrin homology domain containing family G (with RhoGef domain) member 4; member 4; Pleckstrin homology domain-containing family G member 4; PLEKHG 4; PLEKHG4; PRTPHN 1; PRTPHN1; Puratrophin 1; Puratrophin-1; Puratrophin1; Purkinje cell atrophy associated protein 1; Purkinje cell atrophy-associated protein 1; SCA 4; SCA4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 131kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Puratrophin 1/PLEKHG4 (945-105aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5 UTR, or encoding a different isoform, have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Expressed in kidney, Leydig cells in the testis, epithelial cells in the prostate gland and Langerhans islet in the pancreas. Isoform 1 and isoform 3 are strongly expressed in Purkinje cells and to a lower extent in other neurons (at protein level). Widely expressed at low levels. More strongly expressed in testis and pancreas.
Tissue Specificity:
Expressed in kidney, Leydig cells in thetestis, epithelial cells in the prostate gland and Langerhans isletin the pancreas. Isoform 1 and isoform 3 are strongly expressed inPurkinje cells and to a lower extent in other neurons (at proteinlevel). Widely expressed at low levels. More strongly expressed intestis and pancreas.
Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Database links:Entrez Gene: 25894Human
Omim: 609526Human
SwissProt: Q58EX7Human
Unigene: 188781Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.