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货号： bs-0053R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-0053R-AF555
- 英文名称
- Anti-Caspase-13 + 4/AF555
- 中文名称
- AF555标记的半胱胺酸蛋白酶蛋白-13抗体
- 别 名
- CASP-13; CASP4; Caspase 13 subunit 1; Caspase 13 subunit 2; Caspase 4; Caspase 4 subunit 1; Caspase 4, apoptosis related cysteine; CASPD_BOVIN; Caspase-13; Evolutionary related interleukin-1-beta-converting enzyme; ERICE.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from bovine Caspase-13 (71-130aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Caspase-13 (also designated Evolutionarily related interleukin-1beta converting enzyme ; ERICE) involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [subunit] Heterodimer of a small and a large subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. Mainly expressed in peripheral blood lymphocytes, spleen and placenta. Belongs to peptidase family C14.
Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Subunit:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a small and a large subunit (By similarity).
Tissue Specificity:
Mainly expressed in peripheral blood lymphocytes, spleen and placenta.
Similarity:
Belongs to the peptidase C14A family.
Contains 1 CARD domain.
Database links:
Entrez Gene: 338039Cow
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Caspase-13 (也称 Evolutionarily related interleukin-1beta convertingenzyme; ERICE) 参与活化Caspase级联反应，实施调亡。
它既能激活某些蛋白质,细胞死亡所必需的蛋白质；又能使某些蛋白质失活以使细胞能够存活。它的异原二聚体构成大、小两种亚单位，这两种亚单位来源于前体序列由一个自动催化机制而形成或由Caspase-8剪切而成。
Caspase-13主要表达于外周淋巴细胞、脾脏和胎盘。属于肽酶家族C14成员.