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货号： bs-21185R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21185R-HRP
- 英文名称
- Anti-SHISA5/HRP
- 中文名称
- 辣根过氧化物酶标记的SHISA5蛋白抗体
- 别 名
- pProtein shisa 5; Putative NF kappa B activating protein 120; Putative NFkB activating protein 120; Scotin; Shisa homolog 5 (Xenopus laevis); SHSA5_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SHISA5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Function:
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
Subunit:
Interacts with PDCD6; PDCD6 can stabilze SHISA5.
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.
DISEASE:
Induced in a p53/TP53-dependent manner in response to cellular stress
Database links:Entrez Gene: 51246Human
Omim: 607290Human
SwissProt: Q8N114Human
Unigene: 414579Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.