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货号： bs-5466R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5466R-AF555
- 英文名称
- Anti-phospho-JunD (Ser255)/AF555
- 中文名称
- AF555标记的磷酸化活化蛋白激酶D抗体
- 别 名
- JunD (phospho S255); JunD (Phospho Ser255); Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D isoform JunD-FL; Jun-like transcription factor; pfam03957.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 产品类型
- 磷酸化抗体
- 研究领域
- 肿瘤 免疫学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Chicken, Dog, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated Synthesised phosphopeptide derived from human JunD around the phosphorylation site of Ser255
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5-TGA[CG]TCA-3.
Function:
Transcription factor binding AP-1 sites.
Subunit:
Binds DNA as a dimer (By similarity). Interacts with MEN1; this interaction represses transcriptional activation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.
Database links:Entrez Gene: 3727Human
Entrez Gene: 16478Mouse
Entrez Gene: 24518Rat
Omim: 165162Human
SwissProt: P17535Human
SwissProt: P15066Mouse
SwissProt: P52909Rat
Unigene: 2780Human
Unigene: 419851Mouse
Unigene: 46225Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Jun-D属于转录因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD）