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货号： bs-10390R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10390R-AF555
- 英文名称
- Anti-CCDC85B/AF555
- 中文名称
- AF555标记的卷曲螺旋结构域蛋白85B抗体
- 别 名
- Ccdc85b; Coiled coil domain containing 85B; Coiled-coil domain-containing protein 85B; Delta interacting protein A; Delta-interacting protein A; DIPA; Hepatitis delta antigen interacting protein A; Hepatitis delta antigen-interacting protein A; CC85B_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 染色质和核信号 微生物学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 22kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CCDC85B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro. [provided by RefSeq, Jul 2008].
Function:
Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion.
Subunit:
Interacts with CEBPB (By similarity). May interact with CEBPD. Interacts with MCRS1. Interacts with TCF7L2; competes with CTNNB1. Interacts with the viral phosphoprotein hepatitis delta antigen (HDAG). This interaction affects viral genomic replication in intact cells.
Subcellular Location:
Nucleus. Cytoplasm, cytoskeleton, centrosome.
Tissue Specificity:
Widely expressed including liver.
Similarity:
Belongs to the CCDC85 family.
Database links:
NCBI Reference Sequence: NP_006839.2
UniProtKB/Swiss-Prot: Q15834.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.