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货号: bs-5536R-AF555 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-5536R-AF555
- 英文名称
- Anti-TRAK1/AF555
- 中文名称
- AF555标记的驱动蛋白结合蛋白1抗体
- 别 名
- 106 kDa O-GlcNAc transferase-interacting protein; 106 kDa O GlcNAc transferase interacting protein; KIAA1042; OGT(O Glc NAc transferase) interacting protein 106 KDa; OIP106; TRAK1_HUMAN; Trafficking kinesin binding protein 1; Trafficking kinesin-binding protein 1; Trafficking protein kinesin binding 1; TRAK 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 信号转导 细胞骨架 肿瘤细胞生物标志物 线粒体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 106kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TRAK1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The specific function of TRAK1 remains unknown. It interacts with O-GlcNAc transferase, RHOT1/Miro-1 and RHOT2/Miro-2. It shows high expression in spinal cord and moderate expression in all other tissues and specific brain regions examined.
Function:
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors.
Subunit:
Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Interacts with HGS. Interacts with GABRA1. Interacts with KIF5C.
Subcellular Location:
Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome.
Tissue Specificity:
High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.
Post-translational modifications:
O-glycosylated.
Similarity:
Contains 1 HAP1 N-terminal domain.
Database links:Entrez Gene: 22906 Human
Omim: 608112 Human
SwissProt: Q9UPV9 Human
Unigene: 535711 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.