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货号： bs-4277R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4277R-AF555
- 英文名称
- Anti-ENPP7/AF555
- 中文名称
- AF555标记的碱性鞘磷脂酶7抗体
- 别 名
- ALK SMase; Alk-SMase; Alkaline sphingomyelin phosphodiesterase; E-NPP 7; Ectonucleotide pyrophosphatase/phosphodiesterase 7; Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; ENPP7; ENPP7_HUMAN; Intestinal alkaline sphingomyelinase; NPP-7.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 染色质和核信号 细胞周期蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 50kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ENPP7
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.
Function:
Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.
Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential). Note=Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex.
Tissue Specificity:
Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
Post-translational modifications:
N-glycosylated; required for activity and transport to the plasma membrane.
Similarity:
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
Database links:
UniProtKB/Swiss-Prot: Q6UWV6.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.