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货号： bs-5773R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5773R-AF555
- 英文名称
- Anti-FGF22/AF555
- 中文名称
- AF555标记的成纤维细胞生长因子22抗体
- 别 名
- FGF 22; FGF-22; FGF22; FGF22_HUMAN; Fibroblast growth factor 22; si:dkey 21e2.2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 免疫学 信号转导 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FGF22.
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.Fibroblast Growth Factor-22 stimulates the proliferation and activation of cells that express FGF receptor.
Function:
Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.
Subunit:
Interacts with FGFR1 and FGFR2. Interacts with FGFBP1.
Subcellular Location:
Secreted (Potential).
Similarity:
Belongs to the heparin-binding growth factors family.
Database links:Entrez Gene: 27006 Human
Entrez Gene: 67112 Mouse
Entrez Gene: 170579 Rat
Omim: 605831 Human
SwissProt: Q9HCT0 Human
SwissProt: Q9ESS2 Mouse
Unigene: 248087 Human
Unigene: 154211 Mouse
Unigene: 198777 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.