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货号： bs-4950R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4950R-AF555
- 英文名称
- Anti-ERAS/AF555
- 中文名称
- AF555标记的胚胎干细胞RAS蛋白抗体
- 别 名
- E ras; E-Ras; ecat5; Embryonic stem cell expressed Ras; Embryonic stem cell-expressed Ras; Eras; ES cell expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRASP; MGC126691; MGC126693; OTTHUMP00000065857; RASE_HUMAN; Small GTPase protein E Ras; v Ha ras Harvey rat sarcoma viral oncogene homolog pseudogene; v Ha ras Harvey rat sarcoma viral oncogene homolog 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 发育生物学 染色质和核信号 信号转导 干细胞 G蛋白偶联受体 细胞表面分子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ERAS/HRAS2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.
Function:
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity).
Subunit:
Interacts with PIK3CD (By similarity).
Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Similarity:
Belongs to the small GTPase superfamily. Ras family.
Database links:Entrez Gene: 3266Human
Entrez Gene: 353283Mouse
Entrez Gene: 679682Rat
Omim: 300437Human
SwissProt: Q7Z444Human
SwissProt: Q7TN89Mouse
Unigene: 447330Human
Unigene: 250895Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.