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货号： bs-6118R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6118R-AF555
- 英文名称
- Anti-VILIP1/AF555
- 中文名称
- AF555标记的神经视锥蛋白样1抗体(神经钙蛋白)
- 别 名
- VILIP-1; 21 kDa CABP; Hippocalcin like protein 3; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL1; Neural visinin-like protein 1; Neural visinin-like type 1 protein; Neurocalcin alpha; NVL 1; NVL1; Nvp1; OZ1; Ratnvp1; VILIP; Visinin; Visinin like 1; Visinin like protein 1; VISL 1; VISL1; Vnsl1; VISL1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 结合蛋白 Alzheimers
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 22kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human VILIP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Function:
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.
Tissue Specificity:
Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).
Similarity:
Belongs to the recoverin family.
Contains 4 EF-hand domains.
Database links:Entrez Gene: 396189Chicken
Entrez Gene: 282124Cow
Entrez Gene: 7447Human
Entrez Gene: 26950Mouse
Entrez Gene: 100173440Orangutan
Entrez Gene: 24877Rat
Omim: 600817Human
SwissProt: P62764Chicken
SwissProt: P62763Cow
SwissProt: Q4R5F7 Cynomolgus Monkey
SwissProt: P62760Human
SwissProt: P62761Mouse
SwissProt: Q5RD22Orangutan
SwissProt: P62762Rat
Unigene: 444212Human
Unigene: 27005Mouse
Unigene: 105934Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.