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货号： bs-6157R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6157R-AF555
- 英文名称
- Anti-RAB4/AF555
- 中文名称
- AF555标记的癌基因RAS相关蛋白Rab4A抗体
- 别 名
- HRES 1 / RAB4; Oncogene RAB4; OTTHUMP00000042824; Rab 4; RAB 4A; RAB4 member RAS oncogene family; RAB4A; RAB4A member RAS oncogene family; RAB4A_HUMAN; Ras related protein Rab 4A; Ras related protein Rab4A; Ras-related protein Rab-4A.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 G蛋白偶联受体 细胞类型标志物 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RAB4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).
Function:
Protein transport. Probably involved in vesicular traffic (By similarity).
Subunit:
Interacts with SGSM1, SGSM2 and SGSM3 (By similarity). Interacts with RAB11FIP1, RABEP1, ZFYVE20 and RUFY1. Interacts (membrane-bound form) with NDRG1; the interaction involves NDRG1 in vesicular recycling of E-cadherin.
Subcellular Location:
Membrane; Peripheral membrane protein. Cytoplasm. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
Post-translational modifications:
Phosphorylated by CDK1 kinase during mitosis.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
Database links:Entrez Gene: 5867 Human
Entrez Gene: 19341 Mouse
Entrez Gene: 25532 Rat
Omim: 179511 Human
SwissProt: P20338 Human
SwissProt: P56371 Mouse
SwissProt: P05714 Rat
Unigene: 296169 Human
Unigene: 9221 Mouse
Unigene: 3016 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.