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货号： bs-6585R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6585R-AF555
- 英文名称
- Anti-Desmoglein 3/AF555
- 中文名称
- AF555标记的桥粒芯蛋白3抗体
- 别 名
- 130 kD pemphigus vulgaris antigen; Balding; CDHF 6; CDHF6; Desmoglein 3 precursor; Desmoglein3; DKFZp686P23184; DSG 3; DSG3; DSG-3; Pemphigus vulgaris antigen; PVA; DSG3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导 细胞粘附分子 细胞骨架 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 105kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Desmoglein 3 (50-75aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Tissue Specificity:
Epidermis, tongue, tonsil, esophagus and carcinomas.
Similarity:
Contains 4 cadherin domains.
Database links:
UniProtKB/Swiss-Prot: P32926.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.