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货号： bs-6332R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6332R-AF555
- 英文名称
- Anti-ABCA2/AF555
- 中文名称
- AF555标记的三磷酸腺苷结合盒转运蛋白2抗体
- 别 名
- ABC2; ATP binding cassette 2; ATP binding cassette sub family A member 2; ATP binding cassette transporter 2; ATP binding cassette, sub family A (ABC1), member 2; ATP binding cassette, sub family A, member 2; ATP binding cassette, sub family B (MDR/TAP), member 2;ABCA2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学 神经生物学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 270kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ABCA2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene (from EntrezGene).
Function:
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
Subcellular Location:
Endosome. Membrane. Lysosome. Membrane. Forms discrete, punctate intracellular vesicles.
Tissue Specificity:
Highy expressed in the brain, whereas lower levels of expression is observed in kidney and liver.
Similarity:
Belongs to the ABC transporter superfamily. ABCA family.
Contains 2 ABC transporter domains.
Database links:Entrez Gene: 480669 Dog
Entrez Gene: 101132590 Gorilla
Entrez Gene: 100067889 Horse
Entrez Gene: 20 Human
Entrez Gene: 11305 Mouse
Entrez Gene: 79248 Rat
Omim: 600047 Human
SwissProt: Q9BZC7 Human
SwissProt: P41234 Mouse
SwissProt: Q9ESR9 Rat
Unigene: 421202 Human
Unigene: 2210 Mouse
Unigene: 13115 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.