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货号： bs-7640R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7640R-AF555
- 英文名称
- Anti-XKR1/AF555
- 中文名称
- AF555标记的膜转运蛋白XK抗体
- 别 名
- XK; Kell complex 37 kDa component; Membrane transport protein XK; XK related protein 1; XKR1; XRG1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 49kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human XKR1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
XK is the Kell blood group precursor substance. This protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. The Kell blood group is constituted by two covalently linked antigens at the surface of red blood cells, Kell and KX. Whereas Kell is a metalloprotease with demonstrated in vitro enzymatic activity, the role of KX thereon, and/or alone, remains unknown, although its absence is linked to the McLeod syndrome, a neuroacanthocytosis. KX appears to be required for proper synthesis or presentation of the Kell antigens on the red blood cell surface.
Function:
May be involved in sodium-dependent transport of neutral amino acids or oligopeptides
Subunit:
Heterodimer with Kell; disulfide-linked.
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Tissue Specificity:
High levels in skeletal muscle, heart, brain,
DISEASE:
Defects in XK are the cause of McLeod syndrome (MLS) [MIM:300842]. It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems.
Similarity:
Belongs to the XK family.
Database links:Entrez Gene: 7504 Human
Entrez Gene: 22439 Mouse
Entrez Gene: 497078 Rat
Omim: 314850 Human
SwissProt: P51811 Human
SwissProt: Q9QXY7 Mouse
SwissProt: Q5GH61 Rat
Unigene: 78919 Human
Unigene: 56468 Mouse
Unigene: 211877 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.