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货号： bs-7647R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7647R-AF555
- 英文名称
- Anti-VDAC3/AF555
- 中文名称
- AF555标记的线粒体外膜孔蛋白3/电压依赖阴离子通道蛋白3抗体
- 别 名
- hVDAC3; mVDAC3; Outer mitochondrial membrane protein porin 3; voltage dependent anion channel 3; VDAC3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, DogZebrafish,Orangutan
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 31kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human VDAC3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Function:
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).
Subcellular Location:
Mitochondrion outer membrane.
Tissue Specificity:
Widely expressed. Highest in testis.
Similarity:
Belongs to the eukaryotic mitochondrial porin family.
Database links:Entrez Gene: 426793 Chicken
Entrez Gene: 282716 Cow
Entrez Gene: 7419 Human
Entrez Gene: 22335 Mouse
Entrez Gene: 83532 Rat
Omim: 610029 Human
SwissProt: Q9MZ13 Cow
SwissProt: Q9Y277 Human
SwissProt: Q60931 Mouse
SwissProt: Q9TT13 Rabbit
SwissProt: Q9R1Z0 Rat
Unigene: 699301 Human
Unigene: 227704 Mouse
Unigene: 107287 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.