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货号： bs-7683R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7683R-AF555
- 英文名称
- Anti-TReP132/AF555
- 中文名称
- AF555标记的乳腺癌抗雌激素抵抗蛋白2抗体
- 别 名
- BCAR2; Breast cancer anti estrogen resistance 2; Breast cancer anti-estrogen resistance 2; RAPA; rapa 1; rapa 2; rapa1; rapa2; RP1 139D8.5; Transcriptional regulating factor 1; Transcriptional regulating protein 132; Transcriptional-regulating factor 1; Transcriptional-regulating protein 132; TREF1_HUMAN; TReP 132; TREP132; TRERF1; Zinc finger protein rapa; Zinc finger transcription factor TReP 132; Zinc finger transcription factor TReP-132.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 染色质和核信号 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 132kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TReP132/RAPA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.
Function:
Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
Subunit:
Interacts with CREBBP and EP300.
Subcellular Location:
Nucleus.
Tissue Specificity:
Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells.
Similarity:
Contains 3 C2H2-type zinc fingers.
Contains 1 ELM2 domain.
Contains 1 SANT domain.
Database links:Entrez Gene: 55809 Human
Entrez Gene: 224829 Mouse
Entrez Gene: 316219 Rat
Omim: 610322 Human
SwissProt: Q96PN7 Human
SwissProt: Q8BXJ2 Mouse
Unigene: 485392 Human
Unigene: 260989 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.