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货号: bs-7873R-AF555 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-7873R-AF555
- 英文名称
- Anti-S100 alpha 2/AF555
- 中文名称
- AF555标记的S100A2抗体
- 别 名
- S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 细胞周期蛋白 结合蛋白 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Goat, Cat, ,lizard
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 11kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human S100 alpha 2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.
Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.
Subunit:
Homodimer. Interacts with FKBP4.
Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.
Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.
Database links:
UniProtKB/Swiss-Prot: P29034.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.