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货号： bs-8425R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8425R-AF555
- 英文名称
- Anti-BPIL3/AF555
- 中文名称
- AF555标记的杀菌/通透性增加蛋白样3抗体
- 别 名
- Bactericidal/permeability increasing protein like 3; BPIL 3; BPIL-3; LPLUNC6; OTTHUMP00000030617.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 48kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BPIL3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL3 (Bactericidal/permeability-increasing protein-like 3) is a 453 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL3 is primarily expressed at low levels in tonsils, it has been found to be upregulated in hypertrophic tonsil tissue, suggesting that it may play a role in the pathogenesis of inflamed disease tissue.
Subcellular Location:
Secreted (By similarity).
Tissue Specificity:
Detected at very low levels in normal tonsils, and at higher levels in hypertrophic tonsils.
Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Database links:
UniProtKB/Swiss-Prot: Q8NFQ5.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.