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货号： bs-9101R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9101R-AF555
- 英文名称
- Anti-ARSH/AF555
- 中文名称
- AF555标记的芳香基硫酸酯酶H抗体
- 别 名
- Arylsulfatase H; ASH; ARSH_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 62kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ARSH
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling and degradation of macromolecules. Arylsulfatase H, also known as ARSH, is a 562 amino acid protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Localized to the plasma membrane, Arylsulfatase H uses calcium as a cofactor to hydrolyze sulfate esters. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turners syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Post-translational modifications:
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity).
Similarity:
Belongs to the sulfatase family.
Database links:Entrez Gene: 347527 Human
Omim: 300586 Human
SwissProt: Q32KH8 Dog
SwissProt: Q5FYA8 Human
Unigene: 351533 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.