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货号： bs-9198R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9198R-AF555
- 英文名称
- Anti-IGSF6/AF555
- 中文名称
- AF555标记的免疫球蛋白超家族成员6抗体
- 别 名
- DORA; Immunoglobulin superfamily member 6; IGSF6_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IGSF6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
- 产品介绍
- background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF6 (immunoglobulin superfamily, member 6), also known as DORA, is a novel 241 amino acid single-pass type I membrane protein that contains one Ig-like C2-type (immunoglobulin-like) domain. Expressed in spleen, dendritic cells, peripheral blood lymphocytes and lymph node, IGSF6 is induced by TNF?and GM-CSF in dendritic cells and downregulated by ionomycin and PMA in monocytes. IGSF6 may function as a co-receptor in the antigen uptake complex or dendritic cell recirculation and is encoded by a gene located on human chromosome 16p12.2, a locus associated with inflammatory bowel disease.
Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Expressed in peripheral blood lymphocytes, spleen and lymph node, with low levels in thymus, bone marrow and fetal liver. No expression in non-immune tissues.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 10261 Human
Omim: 606222 Human
SwissProt: O95976 Human
Unigene: 530902 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.