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货号： bs-9395R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9395R-AF555
- 英文名称
- Anti-DCAF13/AF555
- 中文名称
- AF555标记的DCAF13蛋白抗体
- 别 名
- DCA13_HUMAN; DCAF13; DDB1 and CUL4 associated factor 13; DDB1- and CUL4-associated factor 13; DKFZP564O0463; GM83; HSPC064; WD repeat and SOF domain-containing protein 1; WD repeats and SOF1 domain containing; WDSOF1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DCAF13
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
Function:
Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Subunit:
Interacts with DDB1.
Subcellular Location:
Nucleus, nucleolus (By similarity).
Similarity:
Contains 7 WD repeats.
Database links:Entrez Gene: 25879 Human
Entrez Gene: 223499 Mouse
Entrez Gene: 100173913 Orangutan
SwissProt: Q5ZLK1 Chicken
SwissProt: Q9NV06 Human
SwissProt: Q6PAC3 Mouse
SwissProt: Q5R4T8 Orangutan
Unigene: 532265 Human
Unigene: 321937 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.