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货号: bs-12748R-HRP 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-12748R-HRP
- 英文名称
- Anti-PNRC2/HRP
- 中文名称
- 辣根过氧化物酶标记的富含脯氨酸核受体共激活因子2抗体
- 别 名
- 0610011E17Rik; D4Bwg0593e; FLJ20312; MGC11707; MGC93828; MGC99541; OTTMUSP00000010360; OTTMUSP00000010366; pnrc2; PNRC2_HUMAN; Proline rich nuclear receptor coactivator 2; Proline-rich nuclear receptor coactivator 2; RP11-4M23.5; RP23-161N17.3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PNRC2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.
Subcellular Location:
Nucleus. Cytoplasm >P-body.
Tissue Specificity:
Expressed in heart, lung, muscle and brain.
Similarity:
Belongs to the PNRC family. PNRC2 subfamily.
Database links:Entrez Gene: 100505603Human
Entrez Gene: 55629Human
Entrez Gene: 52830Mouse
Entrez Gene: 100125373Rat
Omim: 611882Human
SwissProt: Q9NPJ4Human
SwissProt: Q9CR73Mouse
SwissProt: Q66HE1Rat
Unigene: 512636Human
Unigene: 644217Human
Unigene: 716935Human
Unigene: 7862Human
Unigene: 29159Mouse
Unigene: 118788Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.