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货号： bs-9903R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9903R-AF555
- 英文名称
- Anti-SCUBE1/AF555
- 中文名称
- AF555标记的新型血小板相关血管内皮分泌蛋白SCUBE1抗体
- 别 名
- SCUB1_HUMAN; SCUBE 1; SCUBE1; Signal peptide, CUB and EGF-like domain-containing protein 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 内皮细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 105kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SCUBE1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Function:
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Subunit:
Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3.
Subcellular Location:
Secreted. Cell membrane.
Tissue Specificity:
Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.
Post-translational modifications:
N-glycosylated.
Could be proteolytically cleaved to release a smaller active fragment.
Similarity:
Contains 1 CUB domain.
Contains 9 EGF-like domains.
Database links:Entrez Gene: 80274 Human
Entrez Gene: 64706 Mouse
Entrez Gene: 100524621 Pig
Entrez Gene: 315174 Rat
Omim: 611746 Human
SwissProt: Q8IWY4 Human
SwissProt: Q6NZL8 Mouse
Unigene: 133995 Human
Unigene: 40393 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.