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货号： bs-8574R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8574R-AF555
- 英文名称
- Anti-ox-LDL/AF555
- 中文名称
- AF555标记的氧化低密度脂蛋白抗体
- 别 名
- ox-LDL; LDL (Copper oxidized); Cu2SO4 oxidized low density lipoprotein; oxidized low density lipoprotein; Low density lipoprotein; MDA oxidized LDL; MDA oxidized low density lipoprotein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 免疫学 脂蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 31kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- Mouse Cu2+ oxidised low density lipoprotein
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.
Subcellular Location:
Secreted.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
氧化低密度脂蛋白是低密度脂蛋白(low density lipoprotein,LDL)经氧化修饰后形成的,经研究认为:OXLDL的增高与动脉粥样硬化性心血管病(Arteriosclerosis cardiovascular disease,ASCVD)的发生有密切关系。