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货号： bs-11121R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11121R-AF555
- 英文名称
- Anti-PCDHA7/AF555
- 中文名称
- AF555标记的原钙粘附蛋白α7抗体
- 别 名
- CNRS4; PCDA7_HUMAN; PCDH alpha 7; PCDH-alpha-7; PCDHA7; Protocadherin alpha 7; Protocadherin alpha-7.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 98kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PCDHA7
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protein products of PCDH-alpha genes interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA7 (Protocadherin alpha-7) is a 937 amino acid single-pass transmembrane protein that contains six cadherin domains and functions as a potential calcium-dependent cell-adhesion protein, possibly playing a role in the creation and maintenance of neuronal connections. There are two isoforms of PCDHA7 that are produced as a result of alternative splicing events.
Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subunit:
Contains 6 cadherin domains.
Subcellular Location:
Cell membrane.
Similarity:
Contains 6 cadherin domains.
Database links:Entrez Gene: 56141 Human
Omim: 606313 Human
SwissProt: Q9UN72 Human
Unigene: 199343 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.