产品中心
当前位置：首页>产品中心Anti-KY/AF555
货号： bs-11174R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11174R-AF555
- 英文名称
- Anti-KY/AF555
- 中文名称
- AF555标记的脊柱侧后凸畸形肽酶抗体
- 别 名
- KY; KY_HUMAN; Kyphoscoliosis peptidase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 发育生物学 神经生物学 细胞粘附分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 75kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse Kyphoscoliosis peptidase
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
KY peptidase (Kyphoscoliosis peptidase) is a 561 amino acid cytoskeleton protease that interacts with several sarcomeric cytoskeletal proteins, including Filamin 2. KY peptidase probably plays a role in the maturation, function and stabilization of the neuromuscular junction. KY-null mouse mutants exhibit distinct irregular subceullular Filamin 2 localization, suggesting that KY peptidase deficiency may be the cause of several types of limb-girdle muscular dystrophies.
Function:
Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC.
Subunit:
Interacts with IGFN1 and FLNC.
Subcellular Location:
Cytoplasm
Tissue Specificity:
Specifically expressed in skeletal and cardiac muscle.
Similarity:
Belongs to the transglutaminase-like superfamily.
Database links:Entrez Gene: 339855Human
Entrez Gene: 16716Mouse
Omim: 605739Human
SwissProt: Q8NBH2Human
SwissProt: Q8C8H8Mouse
Unigene: 146730Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.