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货号： bs-14369R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14369R
- 英文名称
- DNAJB11
- 中文名称
- DNAJB11蛋白抗体
- 别 名
- ABBP-2; ABBP2; APOBEC1 binding protein 2; APOBEC1-binding protein 2; DJ9; DJB11_HUMAN; DnaJ (Hsp40) homolog subfamily B member 11; DnaJ homolog subfamily B member 11; DnaJ protein homolog 9; DNAJB11; EDJ; ER associated DNAJ; ER associated dnaJ protein 3; ER associated Hsp40 co chaperone; ER-associated DNAJ; ER-associated dnaJ protein 3; ER-associated Hsp40 co-chaperone; ERdj3; ERJ3; ERj3p; hDj-9; hDj9; HEDJ; Human DnaJ protein 9; PWP1 interacting protein 4; PWP1-interacting protein 4.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DNAJB11:25-130/358
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]
Function:
Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.
Subcellular Location:
Endoplasmic reticulum lumen. Associated with the ER membrane in a C-terminally epitope-tagged construct.
Tissue Specificity:
Widely expressed.
Post-translational modifications:
Contains high-mannose Endo H-sensitive carbohydrates.Cys-169, Cys-171, Cys-193 and Cys-196 form intramolecular disulfide bonds. The preferential partner for each Cys is not known.
Similarity:
Contains 1 J domain.
SWISS:
Q9UBS4
Gene ID:
51726
Database links:Entrez Gene: 51726Human
Entrez Gene: 67838Mouse
Entrez Gene: 360734Rat
Omim: 611341Human
SwissProt: Q9UBS4Human
SwissProt: Q99KV1Mouse
SwissProt: Q6TUG0Rat
Unigene: 317192Human
Unigene: 37516Mouse
Unigene: 477367Mouse
Unigene: 14603Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:293T (Human)Cell Lysate at 40 ug
Primary: Anti-DNAJB11(bs-14369R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 38kD
Observed band size: 38kD
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-DNAJB11 (bs-14369R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 38 kD