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货号： bs-21041R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21041R-HRP
- 英文名称
- Anti-POMZP3/HRP
- 中文名称
- 辣根过氧化物酶标记的POMZP3蛋白抗体
- 别 名
- MGC8359; OTTHUMP00000208707; OTTHUMP00000208708; POM (POM121 homolog rat) and ZP3 fusion; POM (POM121 rat homolog) and ZP3 fusion; POM 121; POM and ZP3 fusion; POM ZP3; POM ZP3 fusion protein; POM-ZP3; POM121 and ZP3 fusion protein; POM121; POM121/ZP3 fusion protein; POMZP 3; POMZP3; POMZP3 fusion protein; POZP3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human POMZP3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3 exons from the ZP3 gene. The 5 end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3 end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Function:
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
Subcellular Location:
Secreted > extracellular space > extracellular matrix and Cell membrane.
Tissue Specificity:
Expressed in spleen, thymus, pancreas, testis, ovary, small intestine, colon and lymphocytes.
Post-translational modifications:
Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
N-glycosylated.
O-glycosylated; removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy.
Database links:Entrez Gene: 22932Human
Omim: 600587Human
SwissProt: Q6PJE2Human
Unigene: 488877Human
Unigene: 712837Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.